MolNFT v1 · #151954 · protein

Crystal structure of the ampc from pseudomonas aeruginosa with 1C

6I30 · Class C beta-lactamase pdc-301: “Crystal structure of the ampc from pseudomonas aeruginosa with 1C”. X-ray diffraction, 1 ligand (C6S), 4 pockets (best druggability 0.55). MolNFT v1 #151954 on GenesisL1: 3D structure, binding sites…

PDB: 6I30
Type: protein
Length: 358 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Class C beta-lactamase pdc-301
UniProt: A0A2Z4BUZ1
Ligands: C6S
Pockets: 4 · best druggability 0.55

Structure

x-ray diffraction · 1 distinct chain · 42% helix, 22% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Class C beta-lactamase pdc-301	protein	358	42% helix, 22% strand	A0A2Z4BUZ1

Ligands and binding sites

C6S · (3R)-3-(cyclohexylcarbonylamino)-2-oxidanyl-3,4-dihydro-1,2-benzoxaborinine-8-carboxylic acid · ligand · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

4 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	203	0.55	0.79	39	C6S
2	129	0.55	0.82	27	empty
3	56	0.34	0.78	16	empty
4	63	0.32	0.75	17	empty

Modifications

Observed in the structure: 1 covalent (covalent ligand).

Compared structures

6I30 · Crystal structure of the AmpC from Pseudomonas aeruginosa with 1C · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt A0A2Z4BUZ1
Elsewhere: RCSB PDB 6I30 · PDBe 6I30 · UniProt A0A2Z4BUZ1

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.