MolNFT v1 · #15192 · protein

Structure of F71N mutant of P18INK4C

1MX2 · Cyclin-dependent kinase 6 inhibitor: “Structure of F71N mutant of P18INK4C”. X-ray diffraction. MolNFT v1 #15192 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 1MX2
Type: protein
Length: 312 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Cyclin-dependent kinase 6 inhibitor
UniProt: P42773

Structure

x-ray diffraction · 2 distinct chains · 50% helix, 1% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Cyclin-dependent kinase 6 inhibitor	protein	156	51% helix, 0% strand	P42773
B	Cyclin-dependent kinase 6 inhibitor	protein	156	50% helix, 1% strand	P42773

Interfaces

1 interface between chains.

A–B · 349 Å² buried · 4 hydrogen bonds · protein-protein

Compared structures

1MX2 · Structure of F71N mutant of p18INK4c · the same entry in another collection · chain A against A, TM-score 1.00
P42773 · AlphaFold monomer V2.0 prediction for cyclin-dependent kinase 4 inhibitor C (P42773) · a predicted model of the same protein · chain A against A, TM-score 0.99

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P42773
Elsewhere: RCSB PDB 1MX2 · PDBe 1MX2 · UniProt P42773

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