MolNFT v1 · #1519 · protein
Structure of the arginine repressor from bacillus stearothermophilus
1B4A: “Structure of the arginine repressor from bacillus stearothermophilus”. X-ray diffraction, 10 pockets (best druggability 0.85). MolNFT v1 #1519 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 1B4A
- Type
- protein
- Length
- 876 residues
- Chains
- 6
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Arginine repressor
- UniProt
- O31408
- Pockets
- 10 · best druggability 0.85
Structure
x-ray diffraction · 1 distinct chain · 46% helix, 23% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B, C, D, E, F | Arginine repressor | protein | 146 | 46% helix, 23% strand | O31408 |
Pockets
10 pockets found on a 1 Å grid, 7 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 934 | 0.85 | 0.86 | 88 | empty |
| 2 | 304 | 0.79 | 0.90 | 37 | empty |
| 3 | 308 | 0.74 | 0.86 | 31 | empty |
| 4 | 96 | 0.59 | 0.87 | 17 | empty |
| 5 | 87 | 0.57 | 0.87 | 17 | empty |
Interfaces
14 interfaces between chains.
- A–F · 981 Ų buried · 7 hydrogen bonds · protein-protein
- B–E · 864 Ų buried · 7 hydrogen bonds · protein-protein
- C–D · 862 Ų buried · 7 hydrogen bonds · protein-protein
- D–E · 529 Ų buried · 3 hydrogen bonds · protein-protein
- A–B · 471 Ų buried · 4 hydrogen bonds · protein-protein
Compared structures
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt O31408
- Elsewhere: RCSB PDB 1B4A · PDBe 1B4A · UniProt O31408
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