MolNFT v1 · #151839 · protein

Crystal structure of redox-inhibited phosphoribulokinase from synechococcus sp. (strain pcc 6301)

6HZK: “Crystal structure of redox-inhibited phosphoribulokinase from synechococcus sp. (strain pcc 6301)”. X-ray diffraction, 5 pockets (best druggability 0.62). MolNFT v1 #151839 on GenesisL1: 3D structure, binding sites and pockets in…

PDB: 6HZK
Type: protein
Length: 624 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Phosphoribulokinase
EC: 2.7.1.19
UniProt: A0A0H3K6J7
Pockets: 5 · best druggability 0.62

Structure

x-ray diffraction · 2 distinct chains · 34% helix, 29% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Phosphoribulokinase (EC 2.7.1.19)	protein	329	36% helix, 28% strand	A0A0H3K6J7
B	Phosphoribulokinase (EC 2.7.1.19)	protein	295	31% helix, 31% strand	A0A0H3K6J7

Pockets

5 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	290	0.62	0.79	36	empty
2	106	0.42	0.77	19	empty
3	101	0.40	0.76	17	empty
4	78	0.31	0.74	19	empty
5	75	0.30	0.74	22	empty

Interfaces

1 interface between chains.

A–B · 935 Å² buried · 31 hydrogen bonds · protein-protein

Modifications

Observed in the structure: 3 disulfide (disulfide).

Compared structures

6HZK · Crystal structure of redox-inhibited phosphoribulokinase from Synechococcus sp. (strain… · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt A0A0H3K6J7
Elsewhere: RCSB PDB 6HZK · PDBe 6HZK · UniProt A0A0H3K6J7

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