MolNFT v1 · #151779 · protein

Crystal structure of the head and coiled-coil domains of zebrafish CCDC61 (F129E/D130A)

6HXV · Coiled-coil domain-containing protein 61: “Crystal structure of the head and coiled-coil domains of zebrafish CCDC61 (F129E/D130A)”. X-ray diffraction, 2 pockets (best druggability 0.37). MolNFT v1 #151779 on GenesisL1: 3D…

PDB: 6HXV
Type: protein
Length: 323 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Coiled-coil domain-containing protein 61
UniProt: Q08CF3
Pockets: 2 · best druggability 0.37

Structure

x-ray diffraction · 2 distinct chains · 37% helix, 37% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Coiled-coil domain-containing protein 61	protein	163	36% helix, 36% strand	Q08CF3
B	Coiled-coil domain-containing protein 61	protein	160	38% helix, 38% strand	Q08CF3

Pockets

2 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	54	0.37	0.80	12	empty
2	63	0.36	0.78	15	empty

Interfaces

1 interface between chains.

A–B · 1148 Å² buried · 10 hydrogen bonds · protein-protein

Compared structures

6HXV · Crystal structure of the head and coiled-coil domains of zebrafish CCDC61 (F129E/D130A) · the same entry in another collection · chain A against A, TM-score 1.00
Q08CF3 · AlphaFold monomer V2.0 prediction for centrosomal protein CCDC61 (Q08CF3) · a predicted model of the same protein · chain A against A, TM-score 0.95

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q08CF3
Elsewhere: RCSB PDB 6HXV · PDBe 6HXV · UniProt Q08CF3

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