MolNFT v1 · #151652 · protein
Phosphorylated F97L hepatitis B core protein capsid
6HU7 · Capsid protein: “Phosphorylated F97L hepatitis B core protein capsid”. Electron microscopy, 7 pockets (best druggability 0.77). MolNFT v1 #151652 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 6HU7
- Type
- protein
- Length
- 609 residues
- Chains
- 7
- Method
- electron microscopy
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Capsid protein
- UniProt
- D0EYZ6
- Pockets
- 7 · best druggability 0.77
Structure
electron microscopy · 5 distinct chains · 64% helix, 0% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| B | Capsid protein | protein | 152 | 64% helix, 0% strand | D0EYZ6 |
| A | Capsid protein | protein | 147 | 65% helix, 0% strand | D0EYZ6 |
| C, D | Capsid protein | protein | 151 | 66% helix, 0% strand | D0EYZ6 |
| F | Capsid protein | protein | 2 | 0% helix, 0% strand | D0EYZ6 |
| G, H | Capsid protein | protein | 3 | 0% helix, 0% strand | D0EYZ6 |
Pockets
7 pockets found on a 1 Å grid, 4 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 129 | 0.77 | 0.95 | 28 | empty |
| 2 | 318 | 0.72 | 0.84 | 42 | empty |
| 3 | 143 | 0.67 | 0.88 | 18 | empty |
| 4 | 125 | 0.64 | 0.87 | 21 | empty |
| 5 | 69 | 0.30 | 0.73 | 15 | empty |
Interfaces
6 interfaces between chains.
- C–D · 2052 Ų buried · 18 hydrogen bonds · protein-protein
- B–A · 2047 Ų buried · 15 hydrogen bonds · protein-protein
- B–C · 1142 Ų buried · 9 hydrogen bonds · protein-protein
- D–H · 206 Ų buried · 7 hydrogen bonds · protein-protein
- C–G · 167 Ų buried · 0 hydrogen bonds · protein-protein
Compared structures
- 6HU7 · phosphorylated F97L Hepatitis B core protein capsid · the same entry in another collection · chain B against B, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt D0EYZ6
- Elsewhere: RCSB PDB 6HU7 · PDBe 6HU7 · UniProt D0EYZ6
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