MolNFT v1 · #151620 · protein
Crystal structure of glutathione transferase XI 3 mutant C56S from trametes versicolor
6HTA · Glutathione transferase XI 3 C56S: “Crystal structure of glutathione transferase XI 3 mutant C56S from trametes versicolor”. X-ray diffraction, 3 pockets (best druggability 0.75). MolNFT v1 #151620 on GenesisL1: 3D structure…
- PDB
- 6HTA
- Type
- protein
- Length
- 593 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Glutathione transferase XI 3 C56S
- Pockets
- 3 · best druggability 0.75
Structure
x-ray diffraction · 2 distinct chains · 44% helix, 7% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Glutathione transferase XI 3 C56S | protein | 300 | 43% helix, 7% strand | — |
| B | Glutathione transferase XI 3 C56S | protein | 293 | 44% helix, 8% strand | — |
Ligands and binding sites
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
3 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 254 | 0.75 | 0.89 | 45 | empty |
| 2 | 352 | 0.70 | 0.83 | 37 | ACT |
| 3 | 238 | 0.56 | 0.78 | 27 | empty |
Interfaces
1 interface between chains.
- A–B · 1149 Ų buried · 16 hydrogen bonds · protein-protein
Compared structures
- 6HTA · Crystal structure of glutathione transferase Xi 3 mutant C56S from Trametes versicolor · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Elsewhere: RCSB PDB 6HTA · PDBe 6HTA
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