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MolNFT v1 · #15128 · protein

NMR structure of the tumor suppressor BIN1: alternative splicing in melanoma and interaction with C-myc

1MV3 · Myc box dependent interacting protein 1: “NMR structure of the tumor suppressor BIN1: alternative splicing in melanoma and interaction with C-myc”. Solution nmr, 1 pocket (best druggability 0.50). MolNFT v1 #15128 on GenesisL1: 3D…

PDB
1MV3
Type
protein
Length
213 residues
Chains
1
Method
solution nmr
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule
Myc box dependent interacting protein 1
UniProt
O00499
Pockets
1 · best druggability 0.50

Structure

solution nmr · 1 distinct chain · 7% helix, 12% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
AMyc box dependent interacting protein 1protein2137% helix, 12% strandO00499

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
11390.500.7922empty

Compared structures

  • 1MV3 · NMR structure of the tumor suppressor BIN1: alternative splicing in melanoma and… · the same entry in another collection · chain A against A, TM-score 1.00
  • O00499 · AlphaFold monomer V2.0 prediction for myc box-dependent-interacting protein 1 (O00499) · a predicted model of the same protein · chain A against A, TM-score 0.36

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