MolNFT v1 · #151000 · RNA

The structure of the SAM/SAH-binding riboswitch.

6HAG · SAM riboswitch: “The structure of the SAM/SAH-binding riboswitch.”. Solution nmr, 1 ligand (SAH), 2 pockets (best druggability 0.36). MolNFT v1 #151000 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 6HAG
Type: RNA
Length: 43 nucleotides
Chains: 1
Method: solution nmr
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: SAM riboswitch
Ligands: SAH
Pockets: 2 · best druggability 0.36

Structure

solution nmr · 1 distinct chain.

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	SAM riboswitch	rna	43	—	—

Ligands and binding sites

SAH · S-adenosyl-L-homocysteine · ligand · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

2 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	113	0.36	0.74	13	SAH
2	54	0.22	0.72	9	empty

Compared structures

6HAG · The structure of the SAM/SAH-binding riboswitch. · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Elsewhere: RCSB PDB 6HAG · PDBe 6HAG

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