MolNFT v1 · #150913 · protein
First X-ray structure of full-length human ruvb-like 2.
6H7X: “First X-ray structure of full-length human ruvb-like 2.”. X-ray diffraction, 1 ligand (MG), 4 pockets (best druggability 0.48). MolNFT v1 #150913 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 6H7X
- Type
- protein
- Length
- 371 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Ruvb-like 2
- EC
- 3.6.4.12
- UniProt
- Q9Y230
- Ligands
- MG
- Pockets
- 4 · best druggability 0.48
Structure
x-ray diffraction · 1 distinct chain · 45% helix, 23% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Ruvb-like 2 (EC 3.6.4.12) | protein | 371 | 45% helix, 23% strand | Q9Y230 |
Ligands and binding sites
- MG · Magnesium ion · metal · 3 copies · chains A
- EDO · 1,2-ethanediol · additive · 7 copies · chains A
- PEG · Di(hydroxyethyl)ether · additive · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
4 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 66 | 0.48 | 0.84 | 17 | empty |
| 2 | 193 | 0.47 | 0.74 | 22 | empty |
| 3 | 137 | 0.44 | 0.76 | 23 | empty |
| 4 | 182 | 0.44 | 0.74 | 28 | EDO |
Compared structures
- 6H7X · First X-ray structure of full-length human RuvB-Like 2. · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q9Y230
- Elsewhere: RCSB PDB 6H7X · PDBe 6H7X · UniProt Q9Y230
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