MolNFT v1 · #150891 · protein

Structure of leishmania PABP1 (domain J).

6H7A · PABP1 domain J: “Structure of leishmania PABP1 (domain J).”. X-ray diffraction, 1 pocket (best druggability 0.50). MolNFT v1 #150891 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 6H7A
Type: protein
Length: 159 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: PABP1 domain J
UniProt: E9AFX7
Pockets: 1 · best druggability 0.50

Structure

x-ray diffraction · 2 distinct chains · 70% helix, 0% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	PABP1 domain J	protein	80	71% helix, 0% strand	E9AFX7
B	PABP1 domain J	protein	79	70% helix, 0% strand	E9AFX7

Pockets

1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	222	0.50	0.75	25	empty

Interfaces

1 interface between chains.

A–B · 342 Å² buried · 1 hydrogen bond · protein-protein

Modifications

Observed in the structure: 1 disulfide (disulfide).

Compared structures

6H7A · Structure of Leishmania PABP1 (domain J). · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt E9AFX7
Elsewhere: RCSB PDB 6H7A · PDBe 6H7A · UniProt E9AFX7

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