High resolution structure of MET1 from mycobacterium hassiacum in complex with 3-methoxy-1,2-propanediol.

Structure

x-ray diffraction · 1 distinct chain · 39% helix, 21% strand (DSSP).

Ligands and binding sites

• FW5 · (2~{S})-3-methoxypropane-1,2-diol · ligand · chains A
• SAH · S-adenosyl-L-homocysteine · ligand · chains A
• MG · Magnesium ion · metal · 2 copies · chains A
• CL · Chloride ion · ion · chains A
• GOL · Glycerol · additive · 4 copies · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Compared structures

• 6H40 · High resolution structure of MeT1 from Mycobacterium hassiacum in complex with… · the same entry in another collection · chain A against A, TM-score 1.00
• K5B7F3 · AlphaFold monomer V2.0 prediction for mmp 1-O-methyltransferase (K5B7F3) · a predicted model of the same protein · chain A against A, TM-score 0.97

Analyse

• Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
• Every structure of UniProt K5B7F3
• Elsewhere: RCSB PDB 6H40 · PDBe 6H40 · UniProt K5B7F3