MolNFT v1 · #15067 · protein
Crystal structure of the tricorn interacting factor selenomethionine-F1
1MT3 · Proline iminopeptidase: “Crystal structure of the tricorn interacting factor selenomethionine-F1”. X-ray diffraction, 2 pockets (best druggability 0.73). MolNFT v1 #15067 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 1MT3
- Type
- protein
- Length
- 293 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Proline iminopeptidase
- EC
- 3.4.11.5
- UniProt
- P96084
- Pockets
- 2 · best druggability 0.73
Structure
x-ray diffraction · 1 distinct chain · 45% helix, 17% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Proline iminopeptidase (EC 3.4.11.5) | protein | 293 | 45% helix, 17% strand | P96084 |
Ligands and binding sites
- MES · 2-(N-morpholino)-ethanesulfonic acid · additive · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
2 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 65 | 0.73 | 0.98 | 22 | MES |
| 2 | 179 | 0.53 | 0.78 | 29 | empty |
Modifications
Observed in the structure: 9 modified, 1 covalent, 1 disulfide (engineered, additive adduct, disulfide).
Compared structures
- 1MT3 · Crystal Structure of the Tricorn Interacting Factor Selenomethionine-F1 · the same entry in another collection · chain A against A, TM-score 1.00
- P96084 · AlphaFold monomer V2.0 prediction for proline iminopeptidase (P96084) · a predicted model of the same protein · chain A against A, TM-score 0.99
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P96084
- Elsewhere: RCSB PDB 1MT3 · PDBe 1MT3 · UniProt P96084
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