MolNFT v1 · #15060 · protein
Crystal structure of MS2 capsids with mutations in the subunit fg loop
1MST · Bacteriophage MS2 capsid: “Crystal structure of MS2 capsids with mutations in the subunit fg loop”. X-ray diffraction, 4 pockets (best druggability 0.76). MolNFT v1 #15060 on GenesisL1: 3D structure, binding sites and pockets in…
- PDB
- 1MST
- Type
- protein
- Length
- 387 residues
- Chains
- 3
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Bacteriophage MS2 capsid
- UniProt
- P03612
- Pockets
- 4 · best druggability 0.76
Structure
x-ray diffraction · 1 distinct chain · 19% helix, 47% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B, C | Bacteriophage MS2 capsid | protein | 129 | 19% helix, 47% strand | P03612 |
Pockets
4 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 979 | 0.76 | 0.78 | 112 | empty |
| 2 | 118 | 0.38 | 0.74 | 26 | empty |
| 3 | 96 | 0.34 | 0.74 | 17 | empty |
| 4 | 53 | 0.33 | 0.77 | 14 | empty |
Interfaces
3 interfaces between chains.
- B–C · 569 Ų buried · 11 hydrogen bonds · protein-protein
- A–B · 545 Ų buried · 5 hydrogen bonds · protein-protein
- A–C · 521 Ų buried · 6 hydrogen bonds · protein-protein
Compared structures
- 1MST · Crystal structure of MS2 capsids with mutations in the subunit fg loop · the same entry in another collection · chain B against B, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P03612
- Elsewhere: RCSB PDB 1MST · PDBe 1MST · UniProt P03612
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.