MolNFT v1 · #150470 · protein
Structure of the A.THALIANA E1 ufd domain in complex with E2
6GUM · Sumo-conjugating enzyme SCE1: “Structure of the A.THALIANA E1 ufd domain in complex with E2”. X-ray diffraction, 1 pocket (best druggability 0.38). MolNFT v1 #150470 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 6GUM
- Type
- protein
- Length
- 266 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Sumo-conjugating enzyme SCE1; SAE2
- EC
- 2.3.2.-
- UniProt
- Q42551, A0A178VMI9
- Pockets
- 1 · best druggability 0.38
Structure
x-ray diffraction · 2 distinct chains · 29% helix, 24% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Sumo-conjugating enzyme SCE1 (EC 2.3.2.-) | protein | 155 | 34% helix, 19% strand | Q42551 |
| B | SAE2 | protein | 111 | 22% helix, 32% strand | A0A178VMI9 |
Ligands and binding sites
- GOL · Glycerol · additive · chains A, B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 61 | 0.38 | 0.79 | 12 | GOL |
Interfaces
1 interface between chains.
- A–B · 929 Ų buried · 15 hydrogen bonds · protein-protein
Compared structures
- 6GUM · Structure of the A.thaliana E1 UFD domain in complex with E2 · the same entry in another collection · chain A against A, TM-score 1.00
- Q42551 · AlphaFold monomer V2.0 prediction for sumo-conjugating enzyme SCE1 (Q42551) · a predicted model of the same protein · chain A against A, TM-score 0.98
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q42551
- Every structure of UniProt A0A178VMI9
- Elsewhere: RCSB PDB 6GUM · PDBe 6GUM · UniProt Q42551 · UniProt A0A178VMI9
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