Molybdenum storage protein with two occupied ATP binding sites

Structure

x-ray diffraction · 2 distinct chains · 43% helix, 15% strand (DSSP).

Ligands and binding sites

• ATP · Adenosine-5'-triphosphate · ligand · 2 copies · chains B, A
• 8M0 · bis(mu4-oxo)-tetrakis(mu3-oxo)-hexakis(mu2-oxo)-hexadecaoxo-octamolybdenum (VI) · ligand · 2 copies · chains B, A
• MO · Molybdenum atom · metal · 7 copies · chains B, A
• MG · Magnesium ion · metal · chains A
• MOO · Molybdate ion · ion · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

6 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.

Interfaces

1 interface between chains.

• B–A · 2266 Ų buried · 27 hydrogen bonds · protein-protein

Compared structures

• 6GUJ · Molybdenum storage protein with two occupied ATP binding sites · the same entry in another collection · chain B against B, TM-score 1.00
• P84308 · AlphaFold monomer V2.0 prediction for molybdenum storage protein subunit alpha (P84308) · a predicted model of the same protein · chain A against A, TM-score 1.00
• P84253 · AlphaFold monomer V2.0 prediction for molybdenum storage protein subunit beta (P84253) · a predicted model of the same protein · chain B against A, TM-score 0.97

Analyse

• Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
• Every structure of UniProt P84253
• Every structure of UniProt P84308
• Elsewhere: RCSB PDB 6GUJ · PDBe 6GUJ · UniProt P84253 · UniProt P84308