MolNFT v1 · #150377 · protein

Paired immunoglobulin-like receptor B (pirb) or leukocyte immunoglobulin-like receptor subfamily B member 3 (LILRB3) full extracellular domain

6GRQ: “Paired immunoglobulin-like receptor B (pirb) or leukocyte immunoglobulin-like receptor subfamily B member 3…”. X-ray diffraction, 1 ligand (NAG), 3 pockets (best druggability 0.36). MolNFT v1 #150377 on GenesisL1: 3D structure…

PDB: 6GRQ
Type: protein
Length: 536 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Paired immunoglobulin-like receptor B
UniProt: Q8K4V6
Ligands: NAG
Pockets: 3 · best druggability 0.36

Structure

x-ray diffraction · 1 distinct chain · 2% helix, 49% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Paired immunoglobulin-like receptor B	protein	536	2% helix, 49% strand	Q8K4V6

Ligands and binding sites

NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose · sugar · 3 copies · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

3 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	60	0.36	0.78	17	empty
2	99	0.35	0.73	20	empty
3	56	0.28	0.74	15	empty

Modifications

Observed in the structure: 5 disulfide, 2 glycan (disulfide, N-glycosylation).

Compared structures

6GRQ · Paired immunoglobulin-like receptor B (PirB) or Leukocyte immunoglobulin-like receptor… · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q8K4V6
Elsewhere: RCSB PDB 6GRQ · PDBe 6GRQ · UniProt Q8K4V6

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