MolNFT v1 · #150344 · protein

Structure of human heat shock protein 90-alpha N-terminal domain (HSP90-ntd) in complex with ampcpp

6GQR · Heat shock protein HSP 90-alpha: “Structure of human heat shock protein 90-alpha N-terminal domain (HSP90-ntd) in complex with ampcpp”. X-ray diffraction, 2 ligands (APC, MG), 1 pocket (best druggability 0.58). MolNFT v1 #150344 on…

PDB: 6GQR
Type: protein
Length: 224 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Heat shock protein HSP 90-alpha
UniProt: P07900
Ligands: APC, MG
Pockets: 1 · best druggability 0.58

Structure

x-ray diffraction · 1 distinct chain · 42% helix, 21% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Heat shock protein HSP 90-alpha	protein	224	42% helix, 21% strand	P07900

Ligands and binding sites

APC · Diphosphomethylphosphonic acid adenosyl ester · ligand · chains A
MG · Magnesium ion · metal · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	213	0.58	0.80	25	MG, APC

Compared structures

6GQR · Structure of human Heat shock protein 90-alpha N-terminal domain (Hsp90-NTD) in complex… · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P07900
Elsewhere: RCSB PDB 6GQR · PDBe 6GQR · UniProt P07900

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