MolNFT v1 · #150289 · protein

Beta-1,4-galactanase from bacteroides thetaiotaomicron

6GP5 · Arabinogalactan endo-beta-1,4-galactanase: “Beta-1,4-galactanase from bacteroides thetaiotaomicron”. X-ray diffraction, 6 pockets (best druggability 0.66). MolNFT v1 #150289 on GenesisL1: 3D structure, binding sites and pockets in…

PDB: 6GP5
Type: protein
Length: 625 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Arabinogalactan endo-beta-1,4-galactanase
EC: 3.2.1.89
UniProt: Q89YR3
Pockets: 6 · best druggability 0.66

Structure

x-ray diffraction · 2 distinct chains · 40% helix, 19% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Arabinogalactan endo-beta-1,4-galactanase (EC 3.2.1.89)	protein	314	39% helix, 19% strand	Q89YR3
B	Arabinogalactan endo-beta-1,4-galactanase (EC 3.2.1.89)	protein	311	41% helix, 18% strand	Q89YR3

Pockets

6 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	354	0.66	0.81	55	empty
2	301	0.55	0.76	45	empty
3	192	0.49	0.76	33	empty
4	179	0.48	0.76	31	empty
5	57	0.32	0.76	15	empty

Interfaces

1 interface between chains.

A–B · 649 Å² buried · 4 hydrogen bonds · protein-protein

Compared structures

6GP5 · Beta-1,4-galactanase from Bacteroides thetaiotaomicron · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q89YR3
Elsewhere: RCSB PDB 6GP5 · PDBe 6GP5 · UniProt Q89YR3

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.