MolNFT v1 · #150046 · protein

Structure of lytic transglycosylase mlte mutant S75A from E.COLI

6GI4 · Endo-type membrane-bound lytic murein transglycosylase a: “Structure of lytic transglycosylase mlte mutant S75A from E.COLI”. X-ray diffraction, 1 pocket (best druggability 0.32). MolNFT v1 #150046 on GenesisL1: 3D structure…

PDB: 6GI4
Type: protein
Length: 190 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Endo-type membrane-bound lytic murein transglycosylase a
EC: 4.2.2.-
UniProt: P0C960
Pockets: 1 · best druggability 0.32

Structure

x-ray diffraction · 1 distinct chain · 64% helix, 3% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
B	Endo-type membrane-bound lytic murein transglycosylase a (EC 4.2.2.-)	protein	190	64% helix, 3% strand	P0C960

Ligands and binding sites

TRS · 2-amino-2-hydroxymethyl-propane-1,3-diol · additive · chains B

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	59	0.32	0.76	14	TRS

Compared structures

6GI4 · Structure of Lytic Transglycosylase MltE mutant S75A from E.coli · the same entry in another collection · chain B against B, TM-score 1.00
P0C960 · AlphaFold monomer V2.0 prediction for endo-type membrane-bound lytic murein… · a predicted model of the same protein · chain B against A, TM-score 0.95

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P0C960
Elsewhere: RCSB PDB 6GI4 · PDBe 6GI4 · UniProt P0C960

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