MolNFT v1 · #149955 · protein
Structure of garp (LRRC32) in complex with latent TGF-BETA1 and mhg-8 Fab
6GFF: “Structure of garp (LRRC32) in complex with latent TGF-BETA1 and mhg-8 Fab”. X-ray diffraction, 3 ligands (NAG, BMA, MAN). MolNFT v1 #149955 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 6GFF
- Type
- protein
- Length
- 2,953 residues
- Chains
- 14
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- P01137, Q14392
- Ligands
- NAG, BMA, MAN
Structure
x-ray diffraction · 13 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 168 | — | P01137 |
| B, F | — | protein | 112 | — | P01137 |
| C | — | protein | 209 | — | P01137 |
| D | — | protein | 111 | — | P01137 |
| E | — | protein | 222 | — | P01137 |
| G | — | protein | 218 | — | P01137 |
| H | — | protein | 109 | — | P01137 |
| I | — | protein | 551 | — | Q14392 |
| J | — | protein | 493 | — | Q14392 |
| K | — | protein | 212 | — | — |
| L | — | protein | 214 | — | — |
| M | — | protein | 104 | — | — |
| N | — | protein | 118 | — | — |
Ligands and binding sites
- NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose · sugar · 14 copies · chains I, J
- BMA · beta-D-mannopyranose · sugar · 6 copies
- MAN · alpha-D-mannopyranose · sugar
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 6GFF · Structure of GARP (LRRC32) in complex with latent TGF-beta1 and MHG-8 Fab · the same entry in another collection · chain N against N, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P01137
- Every structure of UniProt Q14392
- Elsewhere: RCSB PDB 6GFF · PDBe 6GFF · UniProt P01137 · UniProt Q14392
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