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MolNFT v1 · #149949 · protein

Molecular basis of egg coat filament cross-linking: structure of the glycosylated ZP1 zp-N1 domain homodimer

6GF8 · Zona pellucida sperm-binding protein 1,ZONA pellucida…: “Molecular basis of egg coat filament cross-linking: structure of the glycosylated ZP1 zp-N1 domain homodimer”. X-ray diffraction, 2 ligands (NAG, FUC). MolNFT v1 #149949 on…

PDB
6GF8
Type
protein
Length
208 residues
Chains
2
Method
x-ray diffraction
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule
Zona pellucida sperm-binding protein 1,ZONA pellucida sperm-binding protein 1
UniProt
A0A140JXP0
Ligands
NAG, FUC

Structure

x-ray diffraction · 2 distinct chains · 0% helix, 58% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
AZona pellucida sperm-binding protein 1,ZONA pellucida sperm-binding protein 1protein1030% helix, 58% strandA0A140JXP0
BZona pellucida sperm-binding protein 1,ZONA pellucida sperm-binding protein 1protein1050% helix, 57% strandA0A140JXP0

Ligands and binding sites

  • NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose · sugar · 4 copies · chains A, B
  • FUC · alpha-L-fucopyranose · sugar · chains A
  • MPD · (4S)-2-methyl-2,4-pentanediol · additive · 4 copies · chains A, B

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Interfaces

1 interface between chains.

  • A–B · 382 Ų buried · 5 hydrogen bonds · protein-protein

Modifications

Observed in the structure: 4 disulfide, 2 glycan (disulfide, N-glycosylation).

Compared structures

  • 6GF8 · Molecular basis of egg coat filament cross-linking: structure of the glycosylated ZP1… · the same entry in another collection · chain A against A, TM-score 1.00

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