MolNFT v1 · #149849 · protein

Crystal structure of glutathione transferase XI 3 from trametes versicolor in complex with glutathione

6GCB: “Crystal structure of glutathione transferase XI 3 from trametes versicolor in complex with glutathione”. X-ray diffraction, 1 ligand (GSH), 3 pockets (best druggability 0.75). MolNFT v1 #149849 on GenesisL1: 3D structure, binding…

PDB: 6GCB
Type: protein
Length: 584 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Glutathione transferase XI 3 from trametes versicolor
Ligands: GSH
Pockets: 3 · best druggability 0.75

Structure

x-ray diffraction · 2 distinct chains · 46% helix, 8% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Glutathione transferase XI 3 from trametes versicolor	protein	293	45% helix, 8% strand	—
B	Glutathione transferase XI 3 from trametes versicolor	protein	291	46% helix, 8% strand	—

Ligands and binding sites

GSH · Glutathione · ligand · 2 copies · chains A, B

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

3 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	250	0.75	0.89	46	empty
2	406	0.62	0.77	37	GSH
3	295	0.54	0.75	34	GSH

Interfaces

1 interface between chains.

A–B · 1144 Å² buried · 16 hydrogen bonds · protein-protein

Compared structures

6GCB · Crystal structure of glutathione transferase Xi 3 from Trametes versicolor in complex… · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Elsewhere: RCSB PDB 6GCB · PDBe 6GCB

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