Crystal structure of a parallel six-helix coiled coil cc-TYPE2-fi

Structure

x-ray diffraction · 1 distinct chain · 93% helix, 0% strand (DSSP).

Ligands and binding sites

• ACE · Acetyl group · ligand · 11 copies · chains A, B, C, D, E, F, G, H, I, J, K, L
• NH2 · Amino group · ion · 4 copies · chains B, C, D, I

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Interfaces

24 interfaces between chains.

• J–K · 841 Ų buried · 3 hydrogen bonds · protein-protein
• K–L · 829 Ų buried · 6 hydrogen bonds · protein-protein
• D–E · 818 Ų buried · 2 hydrogen bonds · protein-protein
• H–I · 800 Ų buried · 4 hydrogen bonds · protein-protein
• G–H · 797 Ų buried · 2 hydrogen bonds · protein-protein

Modifications

Observed in the structure: 11 covalent (covalent ligand).

Compared structures

• 6G6G · Crystal structure of a parallel six-helix coiled coil CC-Type2-FI · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

• Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
• Elsewhere: RCSB PDB 6G6G · PDBe 6G6G