MolNFT v1 · #149608 · protein
Crystal structure of an engineered botulinum neurotoxin type B mutant E1191M/S1199Y in complex with human synaptotagmin 2
6G5G: “Crystal structure of an engineered botulinum neurotoxin type B mutant E1191M/S1199Y in complex with human…”. X-ray diffraction, 1 ligand (MG). MolNFT v1 #149608 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 6G5G
- Type
- protein
- Length
- 1,292 residues
- Chains
- 3
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- P10844, Q8N9I0
- Ligands
- MG
Structure
x-ray diffraction · 3 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 426 | — | P10844 |
| B | — | protein | 848 | — | P10844 |
| P | — | protein | 18 | — | Q8N9I0 |
Ligands and binding sites
- MG · Magnesium ion · metal · chains A
- GOL · Glycerol · additive · 4 copies · chains B
- PEG · Di(hydroxyethyl)ether · additive · 2 copies · chains B
- EDO · 1,2-ethanediol · additive · chains A
- TRS · 2-amino-2-hydroxymethyl-propane-1,3-diol · additive · chains A, B
- ACT · Acetate ion · additive · chains B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 6G5G · Crystal structure of an engineered Botulinum Neurotoxin type B mutant E1191M/S1199Y in… · the same entry in another collection · chain A against A, TM-score 1.00
- P10844 · AlphaFold monomer V2.0 prediction for botulinum neurotoxin type B (P10844) · a predicted model of the same protein · chain A against A, TM-score 0.99
- Q8N9I0 · AlphaFold monomer V2.0 prediction for synaptotagmin-2 (Q8N9I0) · a predicted model of the same protein · chain P against A, TM-score 0.59
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P10844
- Every structure of UniProt Q8N9I0
- Elsewhere: RCSB PDB 6G5G · PDBe 6G5G · UniProt P10844 · UniProt Q8N9I0
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