MolNFT v1 · #149568 · protein
Crystal structure of the omega transaminase from pseudomonas jessenii in the apo form, crystallized from succinate
6G4B · Aspartate aminotransferase family protein: “Crystal structure of the omega transaminase from pseudomonas jessenii in the apo form, crystallized from…”. X-ray diffraction, 6 pockets (best druggability 0.77). MolNFT v1 #149568 on…
- PDB
- 6G4B
- Type
- protein
- Length
- 904 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Aspartate aminotransferase family protein
- UniProt
- A0A2D8IND4
- Pockets
- 6 · best druggability 0.77
Structure
x-ray diffraction · 2 distinct chains · 43% helix, 17% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Aspartate aminotransferase family protein | protein | 451 | 44% helix, 17% strand | A0A2D8IND4 |
| B | Aspartate aminotransferase family protein | protein | 453 | 43% helix, 17% strand | A0A2D8IND4 |
Ligands and binding sites
- SIN · Succinic acid · additive · 2 copies · chains A, B
- GOL · Glycerol · additive · 2 copies · chains A, B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
6 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 888 | 0.77 | 0.80 | 86 | SIN, GOL |
| 2 | 794 | 0.77 | 0.81 | 89 | SIN, GOL |
| 3 | 94 | 0.37 | 0.75 | 19 | empty |
| 4 | 97 | 0.34 | 0.73 | 21 | empty |
| 5 | 58 | 0.30 | 0.75 | 11 | empty |
Interfaces
1 interface between chains.
- A–B · 5467 Ų buried · 92 hydrogen bonds · protein-protein
Compared structures
- 6G4B · Crystal structure of the omega transaminase from Pseudomonas jessenii in the apo form… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt A0A2D8IND4
- Elsewhere: RCSB PDB 6G4B · PDBe 6G4B · UniProt A0A2D8IND4
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