MolNFT v1 · #149407 · protein
Human PARP14 (ARTD8), catalytic fragment in complex with inhibitor ITK6
6FZM: “Human PARP14 (ARTD8), catalytic fragment in complex with inhibitor ITK6”. X-ray diffraction, 1 ligand (EE5). MolNFT v1 #149407 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 6FZM
- Type
- protein
- Length
- 375 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- Q460N5
- Ligands
- EE5
Structure
x-ray diffraction · 2 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 190 | — | Q460N5 |
| B | — | protein | 185 | — | Q460N5 |
Ligands and binding sites
- EE5 · 4-[(8-methyl-4-oxidanylidene-7-prop-1-ynyl-3~{H}-quinazolin-2-yl)methylsulfanyl]benzoic acid · ligand · 2 copies · chains A, B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 6FZM · Human PARP14 (ARTD8), catalytic fragment in complex with inhibitor ITK6 · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q460N5
- Elsewhere: RCSB PDB 6FZM · PDBe 6FZM · UniProt Q460N5
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