MolNFT v1 · #149311 · protein
Crystal structure of human wild type beta-1,4-galactosyltransferase-1 (B4GALT1) in apo-open monomeric form
6FWT · Beta-1,4-galactosyltransferase 1: “Crystal structure of human wild type beta-1,4-galactosyltransferase-1 (B4GALT1) in apo-open monomeric form”. X-ray diffraction, 2 pockets (best druggability 0.49). MolNFT v1 #149311 on GenesisL1…
- PDB
- 6FWT
- Type
- protein
- Length
- 277 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Beta-1,4-galactosyltransferase 1
- EC
- 2.4.1.-, 2.4.1.22, 2.4.1.90, 2.4.1.38
- UniProt
- P15291
- Pockets
- 2 · best druggability 0.49
Structure
x-ray diffraction · 1 distinct chain · 26% helix, 21% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Beta-1,4-galactosyltransferase 1 (EC 2.4.1.-, 2.4.1.22, 2.4.1.90, 2.4.1.38) | protein | 277 | 26% helix, 21% strand | P15291 |
Ligands and binding sites
- GOL · Glycerol · additive · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
2 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 208 | 0.49 | 0.75 | 29 | empty |
| 2 | 71 | 0.42 | 0.80 | 19 | empty |
Modifications
Observed in the structure: 2 disulfide (disulfide).
Compared structures
- 6FWT · Crystal structure of human wild type beta-1,4-galactosyltransferase-1 (B4GalT1) in… · the same entry in another collection · chain A against A, TM-score 1.00
- P15291 · AlphaFold monomer V2.0 prediction for beta-1,4-galactosyltransferase 1 (P15291) · a predicted model of the same protein · chain A against A, TM-score 0.94
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P15291
- Elsewhere: RCSB PDB 6FWT · PDBe 6FWT · UniProt P15291
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.