MolNFT v1 · #149300 · protein

Structure of the GH99 endo-alpha-mannanase from bacteroides xylanisolvens in complex with alpha-glc-1,3-(1,2-anhydro-carba- mannosamine)

6FWI · Glycosyl hydrolase family 71: “Structure of the GH99 endo-alpha-mannanase from bacteroides xylanisolvens in complex with…”. X-ray diffraction, 2 ligands (E9K, GLC), 1 pocket (best druggability 0.48). MolNFT v1 #149300 on GenesisL1…

PDB: 6FWI
Type: protein
Length: 343 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Glycosyl hydrolase family 71
UniProt: D6D1V7
Ligands: E9K, GLC
Pockets: 1 · best druggability 0.48

Structure

x-ray diffraction · 1 distinct chain · 33% helix, 17% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Glycosyl hydrolase family 71	protein	343	33% helix, 17% strand	D6D1V7

Ligands and binding sites

E9K · (1~{R},2~{R},3~{R},4~{R},6~{R})-4-(hydroxymethyl)-7-azabicyclo[4.1.0]heptane-2,3-diol · ligand · chains A
GLC · alpha-D-glucopyranose · sugar · chains A
ACT · Acetate ion · additive · 4 copies · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	152	0.48	0.77	26	E9K, GLC

Compared structures

6FWI · Structure of the GH99 endo-alpha-mannanase from Bacteroides xylanisolvens in complex with… · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt D6D1V7
Elsewhere: RCSB PDB 6FWI · PDBe 6FWI · UniProt D6D1V7

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