MolNFT v1 · #149239 · protein
Complement factor D in complex with the inhibitor N-(3'-(aminomethyl)- [1,1'-biphenyl]-3-yl)-3-methylbutanamide
6FUJ: “Complement factor D in complex with the inhibitor N-(3'-(aminomethyl)…”. X-ray diffraction, 1 ligand (E8B). MolNFT v1 #149239 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 6FUJ
- Type
- protein
- Length
- 1,363 residues
- Chains
- 6
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- P00746
- Ligands
- E8B
Structure
x-ray diffraction · 2 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B, C, D, F | — | protein | 228 | — | P00746 |
| E | — | protein | 223 | — | P00746 |
Ligands and binding sites
- E8B · ~{N}-[3-[3-(aminomethyl)phenyl]phenyl]-3-methyl-butanamide · ligand · 3 copies · chains A, B, C
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- P00746 · AlphaFold monomer V2.0 prediction for complement factor D (P00746) · a predicted model of the same protein · chain B against A, TM-score 0.99
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P00746
- Elsewhere: RCSB PDB 6FUJ · PDBe 6FUJ · UniProt P00746
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