MolNFT v1 · #149195 · protein
Crystal structure of CLK1 in complex with inhibitor 8G
6FT8: “Crystal structure of CLK1 in complex with inhibitor 8G”. X-ray diffraction, 3 ligands (E6T, NA, CL). MolNFT v1 #149195 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 6FT8
- Type
- protein
- Length
- 338 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- P49759
- Ligands
- E6T, NA, CL
Structure
x-ray diffraction · 1 distinct chain.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 338 | — | P49759 |
Ligands and binding sites
- E6T · 3-(3-hydroxyphenyl)-1~{H}-pyrrolo[3,4-g]indol-8-one · ligand · chains A
- NA · Sodium ion · metal · chains A
- CL · Chloride ion · ion · chains A
- EDO · 1,2-ethanediol · additive · 6 copies · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 6FT8 · Crystal structure of CLK1 in complex with inhibitor 8g · the same entry in another collection · chain A against A, TM-score 1.00
- P49759 · AlphaFold monomer V2.0 prediction for dual specificity protein kinase CLK1 (P49759) · a predicted model of the same protein · chain A against A, TM-score 0.98
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P49759
- Elsewhere: RCSB PDB 6FT8 · PDBe 6FT8 · UniProt P49759
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