MolNFT v1 · #149080 · protein

Lytic transglycosylase in action

6FPN · Putative soluble lytic murein transglycosylase: “Lytic transglycosylase in action”. X-ray diffraction, 1 ligand (SO4), 6 pockets (best druggability 0.45). MolNFT v1 #149080 on GenesisL1: 3D structure, binding sites and pockets in…

PDB: 6FPN
Type: protein
Length: 586 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Putative soluble lytic murein transglycosylase
UniProt: Q9JXP1
Ligands: SO4
Pockets: 6 · best druggability 0.45

Structure

x-ray diffraction · 1 distinct chain · 67% helix, 1% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
B	Putative soluble lytic murein transglycosylase	protein	586	67% helix, 1% strand	Q9JXP1

Ligands and binding sites

SO4 · Sulfate ion · ion · 7 copies · chains B

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

6 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	175	0.45	0.75	26	SO4
2	194	0.45	0.74	29	empty
3	113	0.43	0.77	14	empty
4	91	0.38	0.76	17	empty
5	114	0.38	0.74	19	empty

Modifications

Observed in the structure: 1 disulfide (disulfide).

Compared structures

6FPN · Lytic transglycosylase in action · the same entry in another collection · chain B against B, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q9JXP1
Elsewhere: RCSB PDB 6FPN · PDBe 6FPN · UniProt Q9JXP1

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