MolNFT v1 · #149025 · protein

Solution structure of mule deer prion protein with polymorphism S138

6FNV · Major prion protein: “Solution structure of mule deer prion protein with polymorphism S138”. Solution nmr, 1 pocket (best druggability 0.29). MolNFT v1 #149025 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 6FNV
Type: protein
Length: 140 residues
Chains: 1
Method: solution nmr
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Major prion protein
UniProt: Q6VS46
Pockets: 1 · best druggability 0.29

Structure

solution nmr · 1 distinct chain · 48% helix, 3% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Major prion protein	protein	140	48% helix, 3% strand	Q6VS46

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	54	0.29	0.75	14	empty

Modifications

Observed in the structure: 1 disulfide (disulfide).

Compared structures

6FNV · Solution structure of mule deer prion protein with polymorphism S138 · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q6VS46
Elsewhere: RCSB PDB 6FNV · PDBe 6FNV · UniProt Q6VS46

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