MolNFT v1 · #14900 · protein
Thioesterase domain from 6-deoxyerythronolide synthase (debs te), pH 8.5
1MO2 · Erythronolide synthase, modules 5 and 6: “Thioesterase domain from 6-deoxyerythronolide synthase (debs te), pH 8.5”. X-ray diffraction, 2 pockets (best druggability 0.75). MolNFT v1 #14900 on GenesisL1: 3D structure, binding sites…
- PDB
- 1MO2
- Type
- protein
- Length
- 502 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Erythronolide synthase, modules 5 and 6
- EC
- 2.3.1.94
- UniProt
- Q03133
- Pockets
- 2 · best druggability 0.75
Structure
x-ray diffraction · 1 distinct chain · 37% helix, 15% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B | Erythronolide synthase, modules 5 and 6 (EC 2.3.1.94) | protein | 251 | 37% helix, 15% strand | Q03133 |
Pockets
2 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 1189 | 0.75 | 0.77 | 109 | empty |
| 2 | 735 | 0.71 | 0.77 | 66 | empty |
Interfaces
1 interface between chains.
- A–B · 504 Ų buried · 0 hydrogen bonds · protein-protein
Compared structures
- 1MO2 · Thioesterase Domain from 6-Deoxyerythronolide Synthase (DEBS TE), pH 8.5 · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q03133
- Elsewhere: RCSB PDB 1MO2 · PDBe 1MO2 · UniProt Q03133
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