MolNFT v1 · #148953 · protein
Pentapeptide repeat family protein from clostridium botulinum
6FLS: “Pentapeptide repeat family protein from clostridium botulinum”. X-ray diffraction, 2 pockets (best druggability 0.73). MolNFT v1 #148953 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 6FLS
- Type
- protein
- Length
- 865 residues
- Chains
- 4
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Pentapeptide repeat family protein
- UniProt
- A0A0M0A2X5
- Pockets
- 2 · best druggability 0.73
Structure
x-ray diffraction · 2 distinct chains · 11% helix, 40% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B, C | Pentapeptide repeat family protein | protein | 216 | 11% helix, 41% strand | A0A0M0A2X5 |
| D | Pentapeptide repeat family protein | protein | 217 | 11% helix, 40% strand | A0A0M0A2X5 |
Ligands and binding sites
- GOL · Glycerol · additive · 15 copies · chains A, B, D, C
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 895 | 0.73 | 0.77 | 71 | GOL |
| 2 | 55 | 0.35 | 0.78 | 15 | empty |
Interfaces
3 interfaces between chains.
- D–C · 1072 Ų buried · 10 hydrogen bonds · protein-protein
- A–B · 1057 Ų buried · 11 hydrogen bonds · protein-protein
- A–D · 447 Ų buried · 5 hydrogen bonds · protein-protein
Compared structures
- 6FLS · Pentapeptide repeat family protein from Clostridium botulinum · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt A0A0M0A2X5
- Elsewhere: RCSB PDB 6FLS · PDBe 6FLS · UniProt A0A0M0A2X5
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