GL1X · GenesisL1 explorer

MolNFT v1 · #148926 · protein

Crystal structure of zebrafish sirtuin 5 in complex with 3- (PHENYLTHIO)SUCCINYL-CPS1 peptide

6FKZ: “Crystal structure of zebrafish sirtuin 5 in complex with 3- (PHENYLTHIO)SUCCINYL-CPS1 peptide”. X-ray diffraction, 1 ligand (ZN). MolNFT v1 #148926 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB
6FKZ
Type
protein
Length
546 residues
Chains
4
Method
x-ray diffraction
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
UniProt
Q6DHI5
Ligands
ZN

Structure

x-ray diffraction · 3 distinct chains.

ChainMoleculeTypeResiduesSecondary structureUniProt
A—protein264—Q6DHI5
B—protein266—Q6DHI5
E, H—protein8——

Ligands and binding sites

  • ZN · Zinc ion · metal · 2 copies · chains A, B
  • GOL · Glycerol · additive · chains A
  • EPE · 4-(2-hydroxyethyl)-1-piperazine ethanesulfonic acid · additive · chains B

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Compared structures

  • 6FKZ · Crystal structure of zebrafish Sirtuin 5 in complex with 3-(phenylthio)succinyl-CPS1… · the same entry in another collection · chain A against A, TM-score 1.00
  • Q6DHI5 · AlphaFold monomer V2.0 prediction for NAD-dependent protein deacylase sirtuin-5… · a predicted model of the same protein · chain A against A, TM-score 0.94

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