MolNFT v1 · #148719 · protein
Ryegrass mottle virus protease domain
6FEZ · Serine protease domain: “Ryegrass mottle virus protease domain”. X-ray diffraction, 2 pockets (best druggability 0.55). MolNFT v1 #148719 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 6FEZ
- Type
- protein
- Length
- 380 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Serine protease domain
- EC
- 2.7.7.48
- UniProt
- A0MCW0
- Pockets
- 2 · best druggability 0.55
Structure
x-ray diffraction · 2 distinct chains · 13% helix, 44% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Serine protease domain (EC 2.7.7.48) | protein | 189 | 13% helix, 44% strand | A0MCW0 |
| B | Serine protease domain (EC 2.7.7.48) | protein | 191 | 13% helix, 44% strand | A0MCW0 |
Pockets
2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 245 | 0.55 | 0.77 | 44 | empty |
| 2 | 83 | 0.47 | 0.81 | 24 | empty |
Interfaces
1 interface between chains.
- A–B · 514 Ų buried · 3 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 2 disulfide (disulfide).
Compared structures
- 6FEZ · Ryegrass mottle virus protease domain · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt A0MCW0
- Elsewhere: RCSB PDB 6FEZ · PDBe 6FEZ · UniProt A0MCW0
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.