MolNFT v1 · #14862 · protein
Crystal structure of galactose mutarotase from lactococcus lactis complexed with D-fucose
1MMX · Aldose 1-epimerase: “Crystal structure of galactose mutarotase from lactococcus lactis complexed with D-fucose”. X-ray diffraction, 2 ligands (FUC, NA), 5 pockets (best druggability 0.70). MolNFT v1 #14862 on GenesisL1: 3D…
- PDB
- 1MMX
- Type
- protein
- Length
- 685 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Aldose 1-epimerase
- EC
- 5.1.3.3
- UniProt
- Q9ZB17
- Ligands
- FUC, NA
- Pockets
- 5 · best druggability 0.70
Structure
x-ray diffraction · 2 distinct chains · 9% helix, 44% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Aldose 1-epimerase (EC 5.1.3.3) | protein | 339 | 9% helix, 45% strand | Q9ZB17 |
| B | Aldose 1-epimerase (EC 5.1.3.3) | protein | 346 | 9% helix, 43% strand | Q9ZB17 |
Ligands and binding sites
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
5 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 415 | 0.70 | 0.81 | 66 | empty |
| 2 | 171 | 0.60 | 0.83 | 38 | FUC |
| 3 | 158 | 0.60 | 0.83 | 32 | FUC |
| 4 | 106 | 0.33 | 0.72 | 20 | empty |
| 5 | 50 | 0.31 | 0.77 | 12 | empty |
Interfaces
1 interface between chains.
- A–B · 1009 Ų buried · 19 hydrogen bonds · protein-protein
Compared structures
- 1MMX · Crystal structure of galactose mutarotase from Lactococcus lactis complexed with D-fucose · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q9ZB17
- Elsewhere: RCSB PDB 1MMX · PDBe 1MMX · UniProt Q9ZB17
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