MolNFT v1 · #148525 · protein

Solution structure of the ring domain of the E3 ubiquitin ligase HRD1

6F98 · E3 ubiquitin-protein ligase: “Solution structure of the ring domain of the E3 ubiquitin ligase HRD1”. Solution nmr, 1 ligand (ZN), 1 pocket (best druggability 0.35). MolNFT v1 #148525 on GenesisL1: 3D structure, binding sites and…

PDB: 6F98
Type: protein
Length: 78 residues
Chains: 1
Method: solution nmr
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: E3 ubiquitin-protein ligase
UniProt: A0A250WAY8
Ligands: ZN
Pockets: 1 · best druggability 0.35

Structure

solution nmr · 1 distinct chain · 14% helix, 13% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	E3 ubiquitin-protein ligase	protein	78	14% helix, 13% strand	A0A250WAY8

Ligands and binding sites

ZN · Zinc ion · metal · 2 copies · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	61	0.35	0.77	15	empty

Compared structures

6F98 · Solution structure of the RING domain of the E3 ubiquitin ligase HRD1 · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt A0A250WAY8
Elsewhere: RCSB PDB 6F98 · PDBe 6F98 · UniProt A0A250WAY8

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