MolNFT v1 · #148470 · protein
Crystal structure of human ARS2 residues 171-270 + 408-763
6F7J · Serrate RNA effector molecule homolog: “Crystal structure of human ARS2 residues 171-270 + 408-763”. X-ray diffraction, 2 pockets (best druggability 0.69). MolNFT v1 #148470 on GenesisL1: 3D structure, binding sites and pockets in…
- PDB
- 6F7J
- Type
- protein
- Length
- 415 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Serrate RNA effector molecule homolog
- UniProt
- Q9BXP5
- Pockets
- 2 · best druggability 0.69
Structure
x-ray diffraction · 2 distinct chains · 52% helix, 11% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Serrate RNA effector molecule homolog | protein | 97 | 76% helix, 1% strand | Q9BXP5 |
| B | Serrate RNA effector molecule homolog | protein | 318 | 44% helix, 14% strand | Q9BXP5 |
Pockets
2 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 743 | 0.69 | 0.76 | 50 | empty |
| 2 | 217 | 0.50 | 0.76 | 27 | empty |
Interfaces
1 interface between chains.
- A–B · 3010 Ų buried · 29 hydrogen bonds · protein-protein
Compared structures
- 6F7J · Crystal structure of Human ARS2 residues 171-270 + 408-763 · the same entry in another collection · chain A against A, TM-score 1.00
- Q9BXP5 · AlphaFold monomer V2.0 prediction for serrate RNA effector molecule homolog (Q9BXP5) · a predicted model of the same protein · chain B against A, TM-score 0.99
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q9BXP5
- Elsewhere: RCSB PDB 6F7J · PDBe 6F7J · UniProt Q9BXP5
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