MolNFT v1 · #148170 · protein

Anti-CRISPR ACRIIA6 tetragonal form

6EYX: “Anti-CRISPR ACRIIA6 tetragonal form”. X-ray diffraction, 5 pockets (best druggability 0.64). MolNFT v1 #148170 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 6EYX
Type: protein
Length: 360 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: ACRIIA6
Pockets: 5 · best druggability 0.64

Structure

x-ray diffraction · 2 distinct chains · 52% helix, 18% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	ACRIIA6	protein	183	51% helix, 17% strand	—
B	ACRIIA6	protein	177	53% helix, 18% strand	—

Pockets

5 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	194	0.64	0.84	24	empty
2	304	0.52	0.74	34	empty
3	217	0.46	0.74	30	empty
4	61	0.36	0.78	17	empty
5	79	0.33	0.75	13	empty

Interfaces

1 interface between chains.

A–B · 1349 Å² buried · 24 hydrogen bonds · protein-protein

Compared structures

6EYX · Anti-CRISPR AcrIIa6 tetragonal form · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Elsewhere: RCSB PDB 6EYX · PDBe 6EYX

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