MolNFT v1 · #148085 · protein
Oreochromis niloticus CEP120 second C2 domain (C2B) A200P + G307S mutant
6EWI · Centrosomal protein 120: “Oreochromis niloticus CEP120 second C2 domain (C2B) A200P + G307S mutant”. X-ray diffraction, 2 pockets (best druggability 0.33). MolNFT v1 #148085 on GenesisL1: 3D structure, binding sites and pockets in…
- PDB
- 6EWI
- Type
- protein
- Length
- 356 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Centrosomal protein 120
- UniProt
- I3K8D3
- Pockets
- 2 · best druggability 0.33
Structure
x-ray diffraction · 2 distinct chains · 11% helix, 43% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Centrosomal protein 120 | protein | 174 | 11% helix, 44% strand | I3K8D3 |
| B | Centrosomal protein 120 | protein | 182 | 11% helix, 42% strand | I3K8D3 |
Pockets
2 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 51 | 0.33 | 0.77 | 13 | empty |
| 2 | 50 | 0.30 | 0.76 | 15 | empty |
Compared structures
- 6EWI · Oreochromis niloticus CEP120 second C2 domain (C2B) A200P + G307S mutant · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt I3K8D3
- Elsewhere: RCSB PDB 6EWI · PDBe 6EWI · UniProt I3K8D3
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