MolNFT v1 · #147975 · protein

Crystal structure of human gamma-D-crystallin mutant P23T+R36S at 1.2 ångströms resolution

6ETC · Gamma-crystallin D: “Crystal structure of human gamma-D-crystallin mutant P23T+R36S at 1.2 ångströms resolution”. X-ray diffraction, 1 pocket (best druggability 0.24). MolNFT v1 #147975 on GenesisL1: 3D structure, binding sites and…

PDB: 6ETC
Type: protein
Length: 173 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Gamma-crystallin D
UniProt: P07320
Pockets: 1 · best druggability 0.24

Structure

x-ray diffraction · 1 distinct chain · 13% helix, 47% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
X	Gamma-crystallin D	protein	173	13% helix, 47% strand	P07320

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	53	0.24	0.72	11	empty

Compared structures

6ETC · Crystal Structure of Human gamma-D-crystallin Mutant P23T+R36S at 1.2 Angstroms Resolution · the same entry in another collection · chain X against X, TM-score 1.00
P07320 · AlphaFold monomer V2.0 prediction for gamma-crystallin D (P07320) · a predicted model of the same protein · chain X against A, TM-score 0.99

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P07320
Elsewhere: RCSB PDB 6ETC · PDBe 6ETC · UniProt P07320

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