MolNFT v1 · #147904 · protein
Crystal structure of a computationally designed colicin endonuclease and immunity pair COLEDES7/IMDES7
6ER6 · Endonuclease COLEDES7: “Crystal structure of a computationally designed colicin endonuclease and immunity pair COLEDES7/IMDES7”. X-ray diffraction, 2 pockets (best druggability 0.35). MolNFT v1 #147904 on GenesisL1: 3D structure…
- PDB
- 6ER6
- Type
- protein
- Length
- 213 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Endonuclease COLEDES7; Immunity IMDES7
- Pockets
- 2 · best druggability 0.35
Structure
x-ray diffraction · 2 distinct chains · 41% helix, 11% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| B | Endonuclease COLEDES7 | protein | 125 | 31% helix, 18% strand | — |
| A | Immunity IMDES7 | protein | 88 | 56% helix, 2% strand | — |
Pockets
2 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 79 | 0.35 | 0.75 | 20 | empty |
| 2 | 92 | 0.34 | 0.74 | 17 | empty |
Interfaces
1 interface between chains.
- B–A · 746 Ų buried · 10 hydrogen bonds · protein-protein
Compared structures
- 6ER6 · Crystal structure of a computationally designed colicin endonuclease and immunity pair… · the same entry in another collection · chain B against B, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Elsewhere: RCSB PDB 6ER6 · PDBe 6ER6
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