MolNFT v1 · #147840 · protein
Structure of chitinase 42 from trichoderma harzianum
6EPB · Endochitinase 42: “Structure of chitinase 42 from trichoderma harzianum”. X-ray diffraction, 1 ligand (ZN), 3 pockets (best druggability 0.66). MolNFT v1 #147840 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 6EPB
- Type
- protein
- Length
- 389 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Endochitinase 42
- EC
- 3.2.1.14
- UniProt
- P48827
- Ligands
- ZN
- Pockets
- 3 · best druggability 0.66
Structure
x-ray diffraction · 1 distinct chain · 35% helix, 21% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Endochitinase 42 (EC 3.2.1.14) | protein | 389 | 35% helix, 21% strand | P48827 |
Ligands and binding sites
- ZN · Zinc ion · metal · 7 copies · chains A
- EDO · 1,2-ethanediol · additive · 20 copies · chains A
- ACT · Acetate ion · additive · 4 copies · chains A
- IMD · Imidazole · additive · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
3 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 336 | 0.66 | 0.80 | 42 | ZN, ACT, IMD |
| 2 | 55 | 0.45 | 0.84 | 20 | EDO |
| 3 | 52 | 0.30 | 0.76 | 16 | empty |
Compared structures
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P48827
- Elsewhere: RCSB PDB 6EPB · PDBe 6EPB · UniProt P48827
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