MolNFT v1 · #14765 · protein

Solution structure of human BCL-W protein

1MK3 · Apoptosis regulator BCL-W: “Solution structure of human BCL-W protein”. Solution nmr, 3 pockets (best druggability 0.77). MolNFT v1 #14765 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 1MK3
Type: protein
Length: 178 residues
Chains: 1
Method: solution nmr
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Apoptosis regulator BCL-W
UniProt: Q92843
Pockets: 3 · best druggability 0.77

Structure

solution nmr · 1 distinct chain · 64% helix, 0% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Apoptosis regulator BCL-W	protein	178	64% helix, 0% strand	Q92843

Pockets

3 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	531	0.77	0.84	50	empty
2	463	0.67	0.78	56	empty
3	73	0.44	0.81	17	empty

Compared structures

1MK3 · Solution structure of human BCL-W protein · the same entry in another collection · chain A against A, TM-score 1.00
Q92843 · AlphaFold monomer V2.0 prediction for BCL-2-like protein 2 (Q92843) · a predicted model of the same protein · chain A against A, TM-score 0.67

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q92843
Elsewhere: RCSB PDB 1MK3 · PDBe 1MK3 · UniProt Q92843

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.