MolNFT v1 · #147597 · protein

Crystal structure of auto inhibited pot family peptide transporter

6EI3 · Proton-dependent oligopeptide transporter family protein: “Crystal structure of auto inhibited pot family peptide transporter”. X-ray diffraction, 1 ligand (78M), 6 pockets (best druggability 0.78). MolNFT v1 #147597 on GenesisL1…

PDB: 6EI3
Type: protein
Length: 511 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Proton-dependent oligopeptide transporter family protein
Ligands: 78M
Pockets: 6 · best druggability 0.78

Structure

x-ray diffraction · 1 distinct chain · 80% helix, 0% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Proton-dependent oligopeptide transporter family protein	protein	511	80% helix, 0% strand	—

Ligands and binding sites

78M · (2S)-2,3-dihydroxypropyl(7z)-pentadec-7-enoate · ligand · 17 copies · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

6 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	810	0.78	0.81	89	empty
2	318	0.55	0.75	33	78M
3	127	0.48	0.78	24	78M
4	101	0.44	0.79	24	empty
5	81	0.44	0.81	16	empty

Compared structures

6EI3 · Crystal structure of auto inhibited POT family peptide transporter · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Elsewhere: RCSB PDB 6EI3 · PDBe 6EI3

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