MolNFT v1 · #147229 · protein

Crystal structure of human cellular retinol-binding protein 4 in complex with abnormal-cannabidiol (abn-cbd)

6E6K · Retinoid-binding protein 7: “Crystal structure of human cellular retinol-binding protein 4 in complex with abnormal-cannabidiol (abn-cbd)”. X-ray diffraction, 1 ligand (HVD), 1 pocket (best druggability 0.82). MolNFT v1 #147229 on…

PDB: 6E6K
Type: protein
Length: 134 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Retinoid-binding protein 7
UniProt: Q96R05
Ligands: HVD
Pockets: 1 · best druggability 0.82

Structure

x-ray diffraction · 1 distinct chain · 13% helix, 54% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Retinoid-binding protein 7	protein	134	13% helix, 54% strand	Q96R05

Ligands and binding sites

HVD · (1'R,2'R)-5'-methyl-6-pentyl-2'-(prop-1-en-2-yl)-1',2', 3',4'-tetrahydro[1,1'-biphenyl]-2,4-diol · ligand · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	332	0.82	0.91	40	HVD

Compared structures

6E6K · Crystal structure of human cellular retinol-binding protein 4 in complex with… · the same entry in another collection · chain A against A, TM-score 1.00
Q96R05 · AlphaFold monomer V2.0 prediction for retinoid-binding protein 7 (Q96R05) · a predicted model of the same protein · chain A against A, TM-score 0.97

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q96R05
Elsewhere: RCSB PDB 6E6K · PDBe 6E6K · UniProt Q96R05

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.