MolNFT v1 · #147125 · protein
Structure of rorgt in complex with a novel agonist.
6E3G: “Structure of rorgt in complex with a novel agonist.”. X-ray diffraction, 1 ligand (HOJ). MolNFT v1 #147125 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 6E3G
- Type
- protein
- Length
- 506 residues
- Chains
- 4
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- P51449
- Ligands
- HOJ
Structure
x-ray diffraction · 2 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B | — | protein | 245 | — | P51449 |
| C, D | — | protein | 8 | — | — |
Ligands and binding sites
- HOJ · (5R)-6-acetyl-2-methoxy-N-{4-[(2-methoxyphenyl) methoxy]phenyl}-5,6,7,8-tetrahydro-1,6-naphthyridine-5-carboxamide · ligand · 2 copies · chains A, B
- EDO · 1,2-ethanediol · additive · 2 copies · chains A, B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 6E3G · Structure of RORgt in complex with a novel agonist. · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P51449
- Elsewhere: RCSB PDB 6E3G · PDBe 6E3G · UniProt P51449
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