MolNFT v1 · #146946 · protein
Structure of the monoclinic-2 (monocl-2) crystal form of human apolipoprotein C1
6DXR · Apolipoprotein C-I: “Structure of the monoclinic-2 (monocl-2) crystal form of human apolipoprotein C1”. X-ray diffraction, 1 pocket (best druggability 0.38). MolNFT v1 #146946 on GenesisL1: 3D structure, binding sites and pockets in…
- PDB
- 6DXR
- Type
- protein
- Length
- 107 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Apolipoprotein C-I
- UniProt
- P02654
- Pockets
- 1 · best druggability 0.38
Structure
x-ray diffraction · 2 distinct chains · 92% helix, 0% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Apolipoprotein C-I | protein | 51 | 92% helix, 0% strand | P02654 |
| B | Apolipoprotein C-I | protein | 56 | 91% helix, 0% strand | P02654 |
Ligands and binding sites
- MPD · (4S)-2-methyl-2,4-pentanediol · additive · 2 copies · chains A, B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 128 | 0.38 | 0.74 | 18 | MPD |
Interfaces
1 interface between chains.
- A–B · 753 Ų buried · 8 hydrogen bonds · protein-protein
Compared structures
- 6DXR · Structure of the Monoclinic-2 (Monocl-2) Crystal Form of Human Apolipoprotein C1 · the same entry in another collection · chain A against A, TM-score 1.00
- P02654 · AlphaFold monomer V2.0 prediction for apolipoprotein C-I (P02654) · a predicted model of the same protein · chain A against A, TM-score 0.52
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P02654
- Elsewhere: RCSB PDB 6DXR · PDBe 6DXR · UniProt P02654
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